US-based Al-Hurra TV has reported that Mubarak was flying toward the United Arab Emirates and was expected in Dubai in an hour.
Speculation about the Egyptian leader's exact location rose after a party spokesperson revealed that the country's first family had taken off to Sharm el-Sheikh, a Red Sea resort town where Mubarak maintains a residence.
Protesters in Cairo, meanwhile, have surrounded the presidential palace, calling for a complete removal of Hosni Mubarak's 30-year-rule.